The DWP's DMG gives some guidance on, first of all, deciding if the client is still self employed. There are a series of Qs to be considered at paragraph 15476 in the link below, such as 'Is there a reasonable prospect of work?' and 'Are they engaged in any work-related activities' (such as practice or rehearsal)?
If they are still considered to be s/e, then has there been an interruption to the normal pattern of work (eg closure of venue, illness of fellow musician)? If so, an assessment of income should start from the date of change- see para 15495.
This is the relevant chapter in DMG:
http://www.dwp.gov.uk/publications/dwp/dmg/
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